Research & Development - Resveratrol
NEW ANTI-AGING CHEMICAL: BUILDS MUSCLE & BURNS FAT?
Forget The Gimmicky Pink Pills...
The "Real" MUSCLE BLASTING/SHREDDING Magic Is Found In This Remarkable "Scientifically Backed" Breakthrough...
Let's start this article just by saying that the "breakthrough" compound we will discuss is almost in a class by itself and truly extraordinary! It's not just used for helping build slabs of lean muscle and triggering fat loss either, but also for its beneficial effects for overall health with powerful longevity promoting properties! This stuff truly is Magic... However, no marketing B.S. or girly labels are needed to go along with this one. It sells itself with "real" groundbreaking science. ;-)
Note: We will include a lot of real published studies for your review to substantiate our facts. So enjoy the information!
Ok, we hope that the flashy headline for this article got your attention because this compound is simply revolutionary. The name of this amazing chemical is Resveratrol. In fact, you might have actually heard of it before as it was casually being preached to old women on Dr. Oz or the Oprah show. You probably yawned and immediately changed the channel and thought nothing more of it. I mean, we know that creatine, protein and of course "steroids" can build muscle... So, listening to these reviews about health supplements for aging people might not have immediately captivated your attention. You probably weren't even compelled to even consider it.
Well, this article will shed some light on this amazing compound as it pertains to you, the athlete or bodybuilder, in your quest for the best possible advantages to build your body, enhance your performance and destroy your competition.
Let's Get Down To The Science....
Resveratrol was first discovered as an active polyphenolic agent derived from red wine and later found also in grapes, peanuts and several other foods.
Resveratrol was first made popular by the breakthrough anti-aging studies of Dr. David Sinclair that showed it increased the life span of certain invertebrates. It's Mechanism Of Action ( MOA) for achieving this remarkable life increasing result was due to its powerful role in our cells gene signaling system. More specifically, Resveratrol was found to be a potent activator of the SIRT-1 gene pathway. This gene system regulates a primary natural biological stress response that signals cells to "survive" longer and more efficiently.
In case you didn't know, the (sirtuin-1) SIRT-1 gene pathway is also triggered by calorie restriction, which is the only scientifically "proven" way to extend life span in humans. The way it works is that when our ancestors evolved and lacked food during times of famine, excessive heat, and drought or in between successful hunts, their bodies evolved and were forced to endure these extreme conditions. In fact, when food supply was small, the body needed to conserve energy and heal itself at optimum efficiency to survive. The SIRT-1 gene pathway became the primary biological pathway for this to occur. The individuals that acquired this enhanced SIRT-1 gene/survival mechanism developed an ability to live longer without food and in excessive heat conditions for longer durations, while those without this genetic feature, or a weaker version of it, died off. So ultimately, natural selection over millions of years helped humans and our ancestors develop a survival mechanism that is triggered by the SIRT-1 gene pathway.
Now, in addition to humans, plants also developed this same survival mechanism. And according to the popular work of Dr. Sinclair, they developed it along-side our ancestors on the evolutionary chain. So, while fruits such as grape vines were present in these exact same, very harsh, hot climates that also lacked adequate rain and good soil, they were also developing the same survival mechanism. In fact, in order for the fruits of some of these plants to survive in these harsh conditions, the fruits (that contained the seeds) of these plants, that survived the best, were those that evolved darker pigments that blocked free radicals and damage from scorching hot sunlight. For clarification, the pigments or polyphenol they developed and that we are talking about here is called Resveratrol.
Now, as our human ancestors living in these harsh environments were also experiencing calorie restriction, the only food they might come across were foods that also contained these special pigments. Our animal ancestors themselves began to identify with these pigments as the only available food and the polyphenols became synonymous with the extreme conditions they were experiencing, thus triggering a stress response. So Resveratrol became identified in human ancestor's bodies as a potent stress response inducing compound due to the evolutionary process of natural selection.
Now it's time for a little scientific vocabulary. A Hormetin is the scientific term for compounds that induce a mild cellular stress in animals that signals a cascade of biological adaptation responses. Hormetins mildly stress and therefore cause cells to emit survival signals that direct the entire body to fix itself and heal. These include releasing growth factors, heat shock proteins and even initiating apoptosis (the programmed destruction of weak cells). Dr. Sinclair was quick to coin the term Xeno-hormesis to the more closely describe the ability of a plant based gene pathway "stress response" system that could inversely activate the same or similar survival stress response in animals. This process developed through long and complex evolutionary processes. This is pretty exciting science! So you may be asking yourself, now that we have identified an incredible compound responsible for inducing a potent stress response, how does this pertain to building muscle and burning fat?
Well, we know that the SIRT-1 gene is responsible for triggering a survival response. Now, we also know what the healthiest people in society look like right? They are leaner and more muscular looking than unhealthy people, right? So, the people surviving the best also look the best. Yes, it's true. Epidemiological studies have clearly shown a link to obesity/excess body fat with a myriad of diseases. These epidemiological studies also clearly show a link to better health and longevity in physically stronger and leaner individuals. Plus, all of these healthier, leaner individuals obviously look better without nearly as much illness such as diabetes, cancer and dementia.
So in summary, as the evolutionary process would have it, activation of the SIRT-1 gene makes you survive better. And if you are surviving better, you are looking better. The epidemiologic studies easily prove that. So now, let's break down a few of the exact mechanisms of action in which activation of the SIRT-1 gene makes you more muscular and lose more fat.
SIRT-1 Gene Activation Induces:
- Metabolism Increase.
In times of extreme stress, the body needed to not only find more food, but also effectively utilize all stored body-fat for fuel. Studies in the lab clearly show increased metabolic markers in a wide variety of animal models. Dr.Sinclair reports of both animal and humans studies that clearly show that Resveratrol's potent SIRT-1 activation triggers much more weight loss than without. What's more exciting for bodybuilders and athletes is that it also can actually help to change your muscle fibers to more resemble those of an elite athlete! That's right! Stronger and more explosive (Fast Twitch) Muscle fibers are more efficient at survival and Resveratrol has been shown to transform Slow twitch muscle tissue into these stronger, faster types! Additionally, Resveratrol has also been shown to induce apoptosis of adipocytes, further enhancing the weight loss process. So Resveratrol helps you build more quality muscle and get leaner, period.
- Heat Shock Proteins Stimulator
Heat Shock Poteins (HSP's) are functional proteins that the body creates during extreme heat and stress as functional proteins that initiate the building of new proteins. Resveratrol has been shown to be a powerful stimulator of Heat Shock Proteins via powerful Xeno-Hormetic activity. Heat Shock Proteins help direct the proper folding and unfolding of proteins to efficiently build muscle tissue. Enhancing this system will only enhance muscle recovery.
- SERM (Selective Estrogen Receptor Modulation)
Resveratrol has been shown to selectively bind with the estrogen receptor to reduce the negative effects of excessive estrogen on certain biological systems, which include bloating, reduced testosterone and soft muscular appearance. Excessive estrogen levels are also linked to an increased occurrence of disease in epidemiological studies. This is possibly due to increased inflammation. Therefore a reduction in excessive estrogen and its related negative effects perfectly correlates with the increased survival response induced by Resveratrol.
- Testosterone Increaser
Via the negative feedback loop of the HPT Axis, the aforementioned reduction in estrogen levels triggers a natural increase in testosterone levels. As we all know, testosterone is a powerful anabolic hormone that can help you build more muscle and strength plus enhances aggressiveness and sexual drive. Primates with higher testosterone levels were more efficient in hunting and also procreation. So increasing testosterone is an important stress response for survival. Again, here is yet another clear connection with enhanced survival response of Resveratrol and humans.
- Inflamation Reducer
Recent science has clearly shown that conditions such as joint discomfort, stiffness and even mental decline are most often times associated with excessive inflammation.Resveratrol and the SIRT-1 gene pathway are associated with enhanced cellular function and thereby triggering a cascade of gene signals that help to reduce inflammation. These include NF-Kappa B Pathway Inhibition.
Resveratrol and Muscle/Fat Burning Summary:
Anecdotal reports from elite athletes that use Muscle Warfare products that are heavily dosed with Resveratrol are definitely reporting of increases in their performance enhancement regimens. This confirms a lot of the science that you read here in the real world. Resveratrol not only aids performance enhancement via multiple pathways, but also enhances overall health. Additionally, its effects on weight loss enhancement are also becoming very clear in the real world as it has been added to Muscle Warfare product to assist in keeping our athletes lean. So ultimately our athletes build high quality muscle, not fat and sloppy gains.
So, what is the effective & safe dose of Resveratrol and how do you get it?
There is a wide range of quality and dosing of Resveratrol containing products on the market. Of course, some better than others, but which ones are best and what dosing is required for the optimal effects? Well, Muscle Warfare researches have performed extensive scientific research on the SIRT-1 gene pathway and Resveratrol's specific activation of this gene pathway. The amount of research and information included in this article alone should demonstrate some of that passion and commitment Muscle Warfare puts into our products. We're committed to discovering the latest technologies for maximum performance enhancement. Muscle Warfare has developed the remarkable ingredient called MYOBOLIC-SERM2. Within this unique ingredient, you find the same commitment to excellence to provide the highest quality Resveratrol extracts available under strict GMP standards. What this basically means is that what we put on the label is what is found in the product at the highest possible purity and dosing possible. Each of Muscle Warfare's flagship products contain a very functional and deliberate dosing of Resveratrol. As each product of The Warfare Stack is taken at different times of the day, the combined use of all the products within The Warfare Stack will result in more SIRT-1 gene activation, translating into enhanced performance enhancement results.
Enhanced Resveratrol Absorption
The MYOBOLIC SERM-2 ingredient in each Muscle Warfare product also contains an esterified version of Resveratrol. By helping bypass first pass liver destruction, the acetyl ester bonded Resveratrol structure is designed to facilitate the absorption of the base compound considerably to increase the overall effectiveness of the formula.
Summary:
Resveratrol is a remarkable compound as is evidenced by an ever growing amount of solid scientific evidence. Muscle Warfare has included this remarkable health enhancing compound in each and every product in the line, including our new fat burner. Be sure to try Muscle Warfare products as quickly as you can to experience the incredible Muscle Building and Fat Burning potential of this incredible compound!
Click here to review a list of the published studies used for validation of the information in this article:
(RESVERATROL)
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